兔单抗-TRAF6BP Antibody

Datasheet

UniProt

Q86VP1

UniProt _link

http://www.uniprot.org/uniprot/Q86VP1

Mol Weight

91kDa

Isotype

Rabbit IgG

Alternative Names

CALCOCO3; D6Ertd404e; D6Ertd772e; PRO0105; T6BP; TAX1BP1; tax1bp1b; TXBP151;

Application

Reactivity

Human Mouse Rat

Dilution

WB 1:500~1:2000 ICC/IF 1:50~1:200

Purification

Affinity-chromatography

Specificity

TRAF6BP Antibody detects endogenous levels of total TRAF6BP

Immunogen

A synthesized peptide derived from human TRAF6BP

Description

Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.

Storage Condition and Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

T58163

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