兔单抗-M6PR Antibody

Datasheet

UniProt

P20645

UniProt _link

http://www.uniprot.org/uniprot/P20645

Mol Weight

42kDa

Isotype

Rabbit IgG

Alternative Names

CD MPR; M6pr; Man6PR; MPR46; MPRD; SMPR;

Application

Reactivity

Human Mouse Rat

Dilution

WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50

Purification

Affinity-chromatography

Specificity

M6PR Antibody detects endogenous levels of total M6PR

Immunogen

A synthesized peptide derived from human M6PR

Description

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Storage Condition and Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

T58686

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