病理诊断与药物研发-ACTH[4E21] mAb

Datasheet

Background

ACTH stimulates secretion of glucocorticoid steroid hormones from adrenal cortex cells, especially in the zona fasciculata of the adrenal glands. ACTH acts by binding to cell surface ACTH receptors, which are located primarily on adrenocortical cells of the adrenal cortex. The ACTH receptor is a seven-membrane-spanning G protein-coupled receptor. Upon ligand binding, the receptor undergoes conformation changes that stimulate the enzyme adenylyl cyclase, which leads to an increase in intracellular cAMP and subsequent activation of protein kinase A.

Antibody Type

Mouse IgG2b

Clone

4E21

Immunogen

Synthetic peptide corresponding to the amino acids 1-39 of human ACTH, conjugated to a high molecular weight carrier

Specificity

Human ACTH

Application

Application

Application

Application

Application

Application

Buffer

Purified : IgG / Liquid
Purfication : Affinity chromatography on Protein G
Buffer system : 10 mM Hepes , 75 mM NaCl , pH 7.5, containing 0.05% Procline 300

Recommanded Dilutions

ELISA                       1:10000-1:5000000

Appendix

Human ACTH ELISA antibody pair 1.pdf

Human ACTH ELISA antibody pair 2.pdf

ELISA抗体配对产品请询价

大量订购请询价

Storage

Stored at -20°C or below until use. Avoid repeated freezing and thawing cycles.

Companion Products

#D10000    PTH[3H19-B]  Mouse mAb
#D10001    PTH[4G4]  Mouse mAb
#T30000    Digoxin[1B9]  Mouse mAb
#T30001    Digoxin[2N7]  Mouse mAb
#T30003    Digoxin[2N7]   mAb (HRP Coujugated)

D10008

货号 规格 价格(¥)
D10008L 200μg
D10008M 100μg
D10008S 50μg

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13162017139(微信同号)

技术支持:13162477137(微信同号)

总机:021-34695901

经销商:QQ 402772198
南方经销商负责:手机13122837132(微信同号)          
北方及西南经销商负责:手机13122150513(微信同号)

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