Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.

COX IV

Cytochrome c oxidase subunit 4 isoform 1, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4

P13073

17 kDa

This Abmart polyclonal antibody is produced by immunizing animals with a polypeptide (Abmart SEAL mAb technology) corresponding to COX IV protein.

Rabbit IgG

Human, Mouse, Rat, Dog, Pig, Cow, Horse

WB 1:500-1:2000 ELISA  1:500-1:1000  IHC-P 1:400-1:800 IHC-F 1:400-1:800  ICC/IF 1:100-1:500

Rabbit IgG in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.