信号通路Signaling-Pan AKT Antibody

Datasheet

Background

Akt, also referred to as PKB or Rac, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration. Akt regulates cellular survival and metabolism by binding and regulating many downstream effectors (e.g.Nuclear Factor-κB, Bcl-2 family proteins, master lysosomal regulator TFEB and murine double minute 2 ).

Source

This Abmart monoclonal antibody is produced by immunizing animals with a polypeptide (Abmart SEAL mAb technology) corresponding to Pan AKT protein.

Protein Name

Pan AKT

UniProt

P31749;P31751;Q9Y243

Alternative Names

PKB;RAC;PRKBA;PKB-ALPHA;RAC-ALPHA; AKT1 ; AKT2; AKT3

Application

Recommend Antibody Dilutions

WB 1:1000 IP 10 tests

Molecular Weight

60KDa

Storage

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Reactivity

Human Mouse Rat

Isotype

Mouse IgG1

T40066

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