经典一抗-DKK3 Antibody

Datasheet

Description

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Alternative Names

Dickkopf 3; Dickkopf 3 homolog (Xenopus laevis); Dickkopf 3 homolog; Dickkopf homolog 3; Dickkopf related protein 3; Dickkopf related protein 3 Precursor; Dickkopf WNT signaling pathway inhibitor 3; Dickkopf, Xenopus, homolog of, 3; Dickkopf-3; Dickkopf-related protein 3; Dickkopf3; DKK 3; Dkk-3; DKK3; DKK3_HUMAN; hDkk 3; hDkk-3; hDkk3; Regulated in glioma; REIC; RIG; RIG-like 5-6; RIG-like 7-1;

Uniprot

Q9UBP4

Uniprot link

Mol Weight

38.3kD; 38kDa(Calculated).

Application

Source

Mouse

Specificity

DKK3 antibody detects endogenous levels of total DKK3.

Reactivity

Human

Application

WB,IHC,ELISA,FCM
 Recommended dilution
WB  1:500-1:2000  IHC  1:50-1:500  ELISA  1:2000  FCM  1:50

Storage

Store at -20 °C. Stable for 12 months from date of receipt.

MB0009

货号 规格 价格(¥)
MB0009M 100μl
MB0009S 50μl

以上产品均有现货供应

订购咨询 orders@ab-mart.com

技术支持 service3@ab-mart.com

订货热线 4006-123-828

经销商名录:点击查看


Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13162017139(微信同号)

技术支持:13162477137(微信同号)

总机:021-34695901

经销商:QQ 402772198
南方经销商负责:手机13122837132(微信同号)          
北方及西南经销商负责:手机13122150513(微信同号)

6380582812748833035900295.jpg

微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13162017139(微信同号)

技术支持:13162477137(微信同号)

总机:021-34695901

经销商:QQ 402772198
南方经销商负责:手机13122837132(微信同号)          
北方及西南经销商负责:手机13122150513(微信同号)

6380582812748833035900295.jpg

微信客服

沪ICP备17056956号-2    艾比玛特医药科技(上海)有限公司