经典一抗-MESP2 Antibody

Datasheet

Description

Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.

Alternative Names

Basic helix loop helix protein MESP 2; Basic helix loop helix protein MESP2; BHLH protein MesP2; bHLHc6; Class C basic helix-loop-helix protein 6; Hypothetical class II basic helix loop helix protein MESP 2; Hypothetical class II basic helix loop helix protein MESP2; Mesoderm posterior 2; mesoderm posterior 2 homolog (mouse); Mesoderm posterior 2 homolog; Mesoderm posterior protein 2; Mesp 2; MESP2; MESP2_HUMAN; SCDO 2; SCDO2;

Uniprot

Q0VG99

Uniprot link

Subcellular location

Nucleus localization

Application

Mol Weight

41.8kD; 42kDa(Calculated).

Source

Mouse

Specificity

MESP2 antibody detects endogenous levels of total MESP2.

Reactivity

Human

Application

WB,ELISA
 Recommended dilution
WB  1:500-1:2000  ELISA  1:2000

Storage

Store at -20 °C. Stable for 12 months from date of receipt.

MB0003

货号 规格 价格(¥)
MB0003M 100μl
MB0003S 50μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13162017139(微信同号)

技术支持:13162477137(微信同号)

总机:021-34695901

经销商:QQ 402772198
南方经销商负责:手机13122837132(微信同号)          
北方及西南经销商负责:手机13122150513(微信同号)

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