Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

C3/C5 convertase; Complement factor B; Glycine-rich beta glycoprotein; PBF2; Properdin factor B;

P00751

86kDa

Mouse monoclonal

Human, Mouse, Rat

WB 1:500-1:2000

Store at -20 °C. Stable for 12 months from date of receipt.