Cell Marker系列-RNF40/BRE1B Mouse Antibody

Datasheet

Background

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Source

This Abmart monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human BRE1B

Protein Name

BRE1B

UniProt

O75150

Alternative Names

95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; BRE1 E3 ubiquitin ligase homolog B; BRE1-B; BRE1B; E3 ubiquitin-protein ligase BRE1B; Rb-associated protein; RBP95; RING finger protein 40; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B; STARING; BRE1B; KIAA0661; RBP95; RNF40; STARING

Application

Predicted Molecular Weight

114 kDa


Western blotting        1:1000-1:5000                     
Immunoprecipitation     10 tests                
FACS                    1:100-1:200

Storage

Store at -20°C, stable for one year from the date of shipment.

Reactivity

Human

Isotype

Mouse IgG

M25085

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