BAK mAb_膜蛋白-

膜蛋白-BAK mAb

Datasheet

Background

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Gene Name

BAK1, BCL2L7, CDN1

Isotype

Mouse IgG

Predicted Mol Weight

24 kDa

Reactivity

Human

Application

Source

This Abmart monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human BAK

Storage

Store at -20°C, stable for one year from the date of shipment.

Recommanded Dilutions

Western blotting 1:1000-1:5000
Immunoprecipitation 10 tests
FACS 1:100-1:200

Alternative Names

Apoptosis regulator BAK; BAK; BAK1; Bcl-2 homologous antagonist/killer; Bcl-2-like protein 7; BCL2-antagonist/killer 1; Bcl2-L-7; BCL2-like 7 protein; BCL2L7; CDN1; cell death inhibitor 1; pro-apoptotic protein BAK