Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER . Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export . Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity). .
Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60) CALR CRTC
Mouse;Rat;Human
WB IHC IF
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Western blotting: 0.2-2μg/mL;1:250-2500 Immunohistochemistry: 5-20μg/mL;1:25-100 Immunocytochemistry: 5-20μg/mL;1:25-100 Optimal working dilutions must be determined by end user.
49kD
CALR CRTC
P27797
Polyclonal
Signal transduction;Metabolic pathway;Bone metabolism;
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Liquid
500μg/mL
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
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应聘职位:hr@ab-mart.com
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销售电话:13162017139(微信同号)
技术支持:15618194176(微信同号)
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南方经销商负责:手机13122837132(微信同号)
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