直标流式抗体-Biotin-Linked Calreticulin (CALR) Antibody

Datasheet

Background收起

Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER . Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export . Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity). .

Alternative Name收起

Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60) CALR CRTC

Reactivity收起

Mouse;Rat;Human

Application收起

WB IHC IF

Application Image收起

  • WB
  • 0

Recommended Dilution收起

Western blotting: 0.2-2μg/mL;1:250-2500 Immunohistochemistry: 5-20μg/mL;1:25-100 Immunocytochemistry: 5-20μg/mL;1:25-100 Optimal working dilutions must be determined by end user.

Mol Weight收起

49kD

Gene Symbol收起

CALR CRTC

Uniprot收起

P27797

Clonality收起

Polyclonal

Research Area收起

Signal transduction;Metabolic pathway;Bone metabolism;

Purification收起

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Formulation收起

Liquid

Concentration收起

500μg/mL

Buffer收起

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Storage收起

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

References

LK48655

货号 规格 价格(¥)
LK48655M 100ul 3,900

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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