13162017139（微信同号）
13162017139（微信同号）
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Glutamate decarboxylase 1 (EC 4.1.1.15) (67 kDa glutamic acid decarboxylase) (GAD-67) (Glutamate decarboxylase 67 kDa isoform) GAD1 GAD GAD67
Human, Mouse, Rat, Dog
IF, IHC, IP, WB
WB 1:500-1:1000, IHC 1:50, IF 1:100, IP: 4ug/mL
66.9 kDa
GAD1 GAD GAD67
Q99259
Full length human recombinant protein of human GAD1 (NP_000808) produced in HEK293T cell.
Mouse
Monoclonal
Mouse IgG
chemical synaptic transmission
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Liquid
0.46 mg/ml
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
艾比玛特医药科技（上海）有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13162017139（微信同号）
技术支持：15618194176（微信同号）
南方经销商负责：手机13122837132(微信同号)
北方及西南经销商负责：手机13122150513(微信同号)
微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13162017139（微信同号）
技术支持：15618194176（微信同号）
总机：021-34695901
南方经销商负责：手机13122837132(微信同号)
北方及西南经销商负责：手机13122150513(微信同号)
微信客服
沪ICP备17056956号-2 艾比玛特医药科技（上海）有限公司
