The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq]

Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171) L1CAM CAML1 MIC5

Human, Mouse, Rat

FC, IF, WB

WB 1:2000, IF 1:100, FLOW 1:100

137.8 kDa

L1CAM CAML1 MIC5

P32004

https://www.uniprot.org/uniprotkb/p32004

Full length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell.

Mouse

Monoclonal

Mouse IgG

Transmembrane

Cell adhesion #Chemotaxis #Neurogenesis

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Liquid

1 mg/ml

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.