Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47) CD47 MER6

Human;Mouse;Rat

WB

WB 1:1000-3000. IF 1:50-200.

35/34/33/32kDa

961

Q08722

https://www.uniprot.org/uniprotkb/Q08722

A synthetic peptide of human CD47

60-110/323aa

Rabbit

Polyclonal

IgG

Angiogenesis #Apoptosis #Inflammatory response #integrin-mediated signaling pathway

Affinity purification

Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.