The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc) NFATC1 NFAT2 NFATC

Human;Mouse;Rat

WB;IHC;IF

WB 1:500-3000.IHC 1:50-200.IF 1:50-200

101/78/89/39kDa

4772

O95644

https://www.uniprot.org/uniprotkb/O95644

Recombinant protein of human NFATC1

Rabbit

Polyclonal

IgG

Cytoplasm Nucleus

Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.