Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

NACHT, LRR and PYD domains-containing protein 10 (Nucleotide-binding oligomerization domain protein 8) NLRP10 NALP10 NOD8 PYNOD

Human Mouse

WB

WB 1:200-1000.

75kDa

338322

Q86W26

https://www.uniprot.org/uniprotkb/Q86W26

A synthetic peptide of human NLRP10

Rabbit

Polyclonal

IgG

Cytoplasm Cell membrane

Adaptive immunity #Inflammatory response #Innate immunity #defense response to fungus

Affinity purification

Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Store at -20℃. Avoid freeze / thaw cycles.