In molecular biology, extracellular signal–regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric G protein-coupled receptors, transforming agents, and carcinogens, activate the ERK pathway. The term, quot;extracellular signal–regulated kinasesquot;, is sometimes used as a synonym for mitogen-activated protein kinase (MAPK).

Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1) MAPK3 ERK1 PRKM3

Human Mouse Rat

WB,IF,IP,FC

Western blotting 1:500-1:2000ICC/IF 1:50-1:200IP 1:50 FC 1:200

42,44kDa

ERK1/2

P27361/P28482

https://www.uniprot.org/uniprotkb/p27361

Rabbit

Monoclonal

Rabbit IgG

Apoptosis #Chondrogenesis #Cell cycle

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2936996