This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants.

Adhesion G-protein coupled receptor G1 (G-protein coupled receptor 56) (Protein TM7XN1) [Cleaved into: ADGRG1 N-terminal fragment (ADGRG1 NT) (GPR56 N-terminal fragment) (GPR56 NT) (GPR56(N)) (GPR56 extracellular subunit) (GPR56 subunit alpha); ADGRG1 C-terminal fragment (ADGRG1 CT) (GPR56 C-terminal fragment) (GPR56 CT) (GPR56(C)) (GPR56 seven-transmembrane subunit) (GPR56 7TM) (GPR56 subunit beta)] ADGRG1 GPR56 TM7LN4 TM7XN1 UNQ540/PRO1083

Human

WB;IHC

WB 1:1000-3000. IHC 1:50-200.

58/78kDa

9289

Q9Y653

https://www.uniprot.org/uniprotkb/Q9Y653

Recombinant protein of human ADGRG1

51-400aa

Rabbit

Polyclonal

IgG

Cytoplasm

Angiogenesis #Cell adhesion #G protein-coupled receptor signaling pathway

Affinity purification

Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.