The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor) PTH1R PTHR PTHR1

Human;Mouse;Rat

WB;IHC

WB 1:2000-5000. IHC 1:25-100.

66kDa

5745

Q03431

https://www.uniprot.org/uniprotkb/Q03431

Recombinant protein of human PTH1R

27-189aa

Rabbit

Polyclonal

IgG

G protein-coupled receptor signaling pathway

Affinity purification

Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.