NFkB-p105 a transcription factor of the nuclear factor-kappaB ( NFkB) group. Undergoes cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of NFkB. NFkB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products.

Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] NFKB1

Human Mouse Rat

Monkey,Dog,Pig,Cat,Horse,Sheep,Bovine,Rabbit,Hamster,Guinea Pig,Chicken,Xenopus

WB,IHC

WB 1:500~1:2000 IHC 1:50~1:200

50kDa/105kDa

NFKB1

p19838

https://www.uniprot.org/uniprotkb/p19838

A synthesized peptide derived from human NF-κB (p105/p50)

Rabbit

Monoclonal

Rabbit IgG

NF-κB (p105/p50) Antibody detects endogenous levels of total NF-κB (p105/p50)

Apoptosis

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.