Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (Nuclear factor, erythroid derived 2, like 2) NFE2L2 NRF2

Human MousePig

WB,IHC,ICC/IF,IP,CHIP

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

70kDa(Calculated);100kDa(Observedinsomecelllines)

NFE2L2 NRF2

q16236

https://www.uniprot.org/uniprotkb/q16236

A synthesized peptide derived from human Nrf2

Rabbit

Monoclonal

Rabbit IgG

Nrf2 Antibody detects endogenous levels of total Nrf2

Inflammatory response

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2936348