The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.

Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) TBK1 NAK

Human Mouse RatPig

WB,IHC,ICC/IF

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

84kDa

TBK1 NAK

q9uhd2

https://www.uniprot.org/uniprotkb/q9uhd2

A synthesized peptide derived from human NAK/TBK1 (N-term)

Rabbit

Monoclonal

Rabbit IgG

NAK/TBK1 (N-term) Antibody detects endogenous levels of total NAK/TBK1 (N-term)

Antiviral defense #Inflammatory response #Innate immunity

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.