The cell division control protein cdc2, also known as cyclin-dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S-phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161.

Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) CDK1 CDC2 CDC28A CDKN1 P34CDC2

Human

WB,IHC,ICC/IF,IP

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

34kDa

CDK1 CDC2 CDC28A CDKN1 P34CDC2

p06493

https://www.uniprot.org/uniprotkb/p06493

A synthesized peptide derived from human CDK1

Rabbit

Monoclonal

Rabbit IgG

CDK1 Antibody detects endogenous levels of total CDK1

Apoptosis #Cell division #DNA condensation #DNA excision #DNA replication

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2936352