CD47 is an integral membrane protein that plays a role in the regulation of cation fluxes across cell membranes. Specifically, CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to the extracellular matrix. It is also a receptor for the C-terminal cell binding domain of thrombospondin (SIRP). CD47 is absent from Rh-null erythrocytes, but does play a role in cell adhesion in non-erythroid cells and may prevent premature elimination of erythrocytes.

Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47) CD47 MER6

Human Mouse Rat

WB,ICC,FCM

WB 1:1000~1:2000 ICC/IF 1:50~1:200 FC 1:50

55kDa

CD47 MER6

q08722

https://www.uniprot.org/uniprotkb/q08722

A synthesized peptide derived from human CD47

Rabbit

Monoclonal

Rabbit IgG

CD47 Antibody detects endogenous levels of total CD47

Transmembrane

Angiogenesis #Apoptosis #Inflammatory response #integrin-mediated signaling pathway

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.