Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Transcription factor SOX-2 SOX2

Human Mouse

WB,IHC,ICC/IF

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

34kDa

SOX2

p48431

https://www.uniprot.org/uniprotkb/p48431

A synthesized peptide derived from human SOX2

Rabbit

Monoclonal

Rabbit IgG

SOX2 Antibody detects endogenous levels of total SOX2

Differentiation #anatomical structure morphogenesis, #chromatin organization

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2892570