Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.

Signal transducer and activator of transcription 3 (Acute-phase response factor) STAT3 APRF

Human Mouse Rat

WB,IHC,ICC/IF

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

88kDa

STAT3 APRF

p40763

https://www.uniprot.org/uniprotkb/p40763

A synthesized peptide derived from human STAT3

Rabbit

Monoclonal

Rabbit IgG

STAT3 Antibody detects endogenous levels of total STAT3

Differentiation #Plant defense #Inflammatory response #defense response

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_3083703