An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.

Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1) MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1

Human Mouse Rat

chickensheep

WB,IHC,ICC/IF,IP,FCM

WB 1:500~1:1000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:30 FC 1:20

289kDa

MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1

p42345

https://www.uniprot.org/uniprotkb/p42345

A synthesized peptide derived from human mTOR

Rabbit

Monoclonal

Rabbit IgG

mTOR Antibody detects endogenous levels of total mTOR

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2936905