Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) AKT1 PKB RAC

Human Mouse Rat

chicken

WB,IHC,ICC/IF,IP,FCM

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

56kDa

AKT1 PKB RAC

p31749

https://www.uniprot.org/uniprotkb/p31749

A synthesized peptide derived from human AKT1/2/3

Rabbit

Monoclonal

Rabbit IgG

AKT1/2/3 Antibody detects endogenous levels of total AKT1/2/3

Sugar transport #Differentiation

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2936969