The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein) ATG7 APG7L

HumanPig

WB,IHC,ICC/IF,IP,FCM

WB 1:10000~1:50000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20 FC 1:20

78kDa

ATG7 APG7L

o95352

https://www.uniprot.org/uniprotkb/o95352

A synthesized peptide derived from human ATG7

Rabbit

Monoclonal

Rabbit IgG

ATG7 Antibody detects endogenous levels of ATG7

Autophagy #Antiviral defense #Protein transport

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.