Oct-4 is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells. Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3) POU5F1 OCT3 OCT4 OTF3

Human Mouse

WB,IHC,ICC/IF,IP

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 ChIP

45kDa

POU5F1 OCT3 OCT4 OTF3

q01860

https://www.uniprot.org/uniprotkb/q01860

A synthesized peptide derived from human Oct4

Rabbit

Monoclonal

Rabbit IgG

Oct4 Antibody detects endogenous levels of Oct4

anatomical structure morphogenesis, #regulation of DNA-templated transcription,

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2892571