Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin) PAX6 AN2

Human Mouse Rat

WB,IHC,ICC/IF

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200

47kDa

PAX6 AN2

p26367

https://www.uniprot.org/uniprotkb/p26367

A synthesized peptide derived from human PAX6

Rabbit

Monoclonal

Rabbit IgG

PAX6 Antibody detects endogenous levels of PAX6

Nucleus localization

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.