Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.

Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein) CDC42

Human Mouse RatChicken

WB,IHC,IP,FCM

WB 1:1000~1:2000 IHC 1:50~1:200 IP 1:30 FC 1:50

21kDa

CDC42

p60953

https://www.uniprot.org/uniprotkb/p60953

A synthesized peptide derived from human CDC42

Rabbit

Monoclonal

Rabbit IgG

CDC42 Antibody detects endogenous levels of total CDC42

Endocytosis

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.