A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable).

Interleukin-18 (IL-18) (Iboctadekin) (Interferon gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma)IL18 IGIF IL1F4

Human, Mouse, Rat

WB,IF/IHC

WB 1:1000-1:2000; IF/IHC1:50-1:200;

22 kDa(Calculated);

IL18 IGIF IL1F4

Q14116

https://www.uniprot.org/uniprotkb/q14116

Rabbit

Polyclonal

Rabbit IgG

IL18 Antibody detects endogenous levels of total IL18.

Angiogenesis #Inflammatory response

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20 °C. Stable for 12 months from date of receipt.