This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit.

Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] CASP8 MCH5

Human,Mouse,Rat

WB,IHC-F,IHC-P,ICC/IF

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Calculated MW: 55 kDa; Observed MW: 43,57 kDa

CASP8

Q14790

Recombinant Protein of Caspase-8

Mouse

Monoclonal

IgG1

Angiogenesis #Apoptosis #B-cell activation

Affinity Purified

Liquid

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Store at 4°C short term. Store at -20°C long term. Avoid freeze/thaw cycles.