IRFs comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response.

Interferon regulatory factor 3 (IRF-3) IRF3

Human,Mouse,Rat

WB,IHC-P,ICC/IF,FC

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

Calculated MW: 47 kDa; Observed MW: 57 kDa

IRF3

Q14653

A synthesized peptide derived from human IRF3

Rabbit

Polyclonal

IgG

Apoptosis #Antiviral defense #DNA damage #Immunity

Affinity Chromatography

Liquid

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Store at 4°C short term. Store at -20°C long term. Avoid freeze/thaw cycles.