Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.

Interleukin-1 beta (IL-1 beta) (Catabolin)IL1B IL1F2

Human, Mouse, Rat

WB,IF/IHC

WB1:1000-1:2000; IF/IHC1:50-1:200

30kD(precursor),17kD(mature);

IL1B IL1F2

P01584

https://www.uniprot.org/uniprotkb/p01584

Rabbit

Polyclonal

Rabbit IgG

IL1bAntibody detects endogenous levels of total IL1b.

Apoptosis

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20 °C. Stable for 12 months from date of receipt.