Thechromatin-specificstatereliesonanucleosomestructurethatvariesdependingonhistonevariants,e.g.H2A.X,H2A.Z,H3.3andCenH3,andoncovalentmodifications,e.g.acetylation,methylation,phosphorylationandubiquitinationonvarioushistoneaminoacidresidues.Nucleosomeassembly,disassemblyandreassemblyarefundamentaltodiverseprocessessuchasDNAreplication,transcriptionandrepair.Becauseoftheirlocationattheperipheryofthenucleosome,histonesH2A/H2BaremoredynamicandneedtoberemovedpriortoH3/H4evictionduringnucleosomedisassembly.Conversely,nucleosomeassembly/reassemblyisinitiatedbyH3/H4deposition,whichisthenfollowedbyH2A/H2Bdeposition.

Probable histone H2AXa (HTA5)At1g08880 F7G19.24

Arabidopsis thaliana, Oryza sativa, Glycine max, Solanum lycopersicum, Solanum tuberosum, Zea mays, Triticum aestivum, Malus pumila Mill, Amygdalus persicaL, Pyrus spp, ect.

WB,IF/IHC

WB1:1000-1:2000; IF/IHC1:50-1:200;

15kD;

At1g08880 F7G19.24

O04848;Q9S9K7;At1g08880;At1g54690

https://www.uniprot.org/uniprotkb/o04848

Rabbit

Polyclonal

Rabbit IgG

Phospho-Histone H2A.X (S139)Antibody detects endogenous levels of total Phospho-Histone H2A.X (S139) .

Nucleus localization

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20 °C. Stable for 12 months from date of receipt.