Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Toll-like receptor 7 TLR7 UNQ248/PRO285

Human

WB,IHC

WB 1:500~1:2000 IHC 1:50~1:200

140kDa(full); 70-75kDa(cleaved, *1*2)

TLR7 UNQ248/PRO285

q9nyk1

https://www.uniprot.org/uniprotkb/q9nyk1

A synthesized peptide derived from human TLR7

Rabbit

Monoclonal

Rabbit IgG

TLR7 Antibody detects endogenous levels of total TLR7

Transmembrane

Antiviral defense  #Inflammatory response  #Innate immunity

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.