Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.

Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) CYP27A1 CYP27

Human Mouse Rat

WB,IHC,ICC/IF,FCM

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:80

50kDa

CYP27A1 CYP27

q02318

https://www.uniprot.org/uniprotkb/q02318

A synthesized peptide derived from human CYP27A1

Rabbit

Monoclonal

Rabbit IgG

CYP27A1 Antibody detects endogenous levels of total CYP27A1

Transmembrane

Cholesterol metabolism

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.