Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.

Low-density lipoprotein receptor-related protein 6 (LRP-6) LRP6

Human Mouse Rat

WB,ICC/IF,FCM

WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50

180-230kDa

LRP6

o75581

https://www.uniprot.org/uniprotkb/o75581

A synthesized peptide derived from human LRP6

Rabbit

Monoclonal

Rabbit IgG

LRP6 Antibody detects endogenous levels of total LRP6

Transmembrane

chemical synaptic transmission

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.