Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity).

Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) SQSTM1 ORCA OSIL

HumanMouse

WB,IHC,ICC/IF,IP,FCM

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

62 kDa

SQSTM1 ORCA OSIL

q13501

https://www.uniprot.org/uniprotkb/q13501

A synthesized peptide derived from human SQSTM1 / p62

Rabbit

Monoclonal

Rabbit IgG

SQSTM1 / p62 Antibody detects endogenous levels of total SQSTM1 / p62

Apoptosis #Autophagy #Differentiation #Immunity

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2936470