Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication- dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3

Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)H3-4 H3FT HIST3H3

Human,Mouse,Rat,Other(WideRange

WB,IHC,IF/ICC,IP,ChIP,CHIP-SEQ

Westernblotting1:500-1:2000 IF/IHC/IP1:50-1:200Chip1:20-1:100

16kD

H3-4 H3FT HIST3H3

Q16695

AsyntheticpeptideofhumanTri-methyl-histoneH3-K4

Rabbit

Polycolonal

RabbitIgg

chromatin organization

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Storeat-20CStablefaroneyearfromthedateofshipment Store at -20°C long term.