Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer's disease.

Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib)LRRC15 LIB

Human, Mouse,Rat

WB

WB1:1000-1:2000; IHC/IF 1:100-1:1000; FACS1:100-1:500

82kDa(Glycosylation). 64kDa(Calculated)

LRRC15 LIB

Q8TF66

https://www.uniprot.org/uniprotkb/q8tf66

Mouse

Monoclonal

Mouse IgG

Lrrc15 Antibody detects endogenous levels of total Lrrc15.

Transmembrane

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20 °C. Stable for 12 months from date of receipt.