Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).

Argonaute-1, isoform A (Argonaute-1, isoform C) (Argonaute-1, isoform D) (LP02696p) (SD07283p)AGO1 Ago AGO-1 Ago-1 Ago1 ago1 ago1-1 AGO1-RC Agp1 anon-WO0257455.29 argonaute1 dAGO1 dAgo1 Dm Ago1 DmAgo1 dmAgo1 Dmel\CG6671 l(2)04845 l(2)4845 l(2)k00208 l(2)k08121 MRE20 CG6671 Dmel_CG6671

Drosophila melanogaster ; Anopheles; migratory locust; Coptotermes formosanus; Laodelphax striatellus; Neodiprion lecontei; Apolygus lucorum; Dinoponera quadriceps; Nasonia vitripennis; Rhodnius prolixus; Frankliniella occidentalis; Thrips palmi; Neodiprion lecontei; Aedes aegypti; Dinoponera quadriceps; Pogonomyrmex barbatus;

WB

WB 1:500-1:2000, IHC 1:50-1:200; IP 1:50-1:100

101 kDa

AGO1 Ago AGO-1 Ago-1 Ago1 ago1 ago1-1 AGO1-RC Agp1 anon-WO0257455.29 argonaute1 dAGO1 dAgo1 Dm Ago1 DmAgo1 dmAgo1 Dmel\CG6671 l(2)04845 l(2)4845 l(2)k00208 l(2)k08121 MRE20 CG6671 Dmel_CG6671

Q32KD4

https://www.uniprot.org/uniprotkb/q32kd4

Mouse

Monoclonal

Mouse IgG

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20 °C. Stable for 12 months from date of receipt.Store at -20°C long term.