This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA,DNA and RNA,RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) G3BP1 G3BP

Human

WB,IP,FACS

Western blotting 1:1000-1:5000 Immunoprecipitation 10 tests FACS 1:100-1:200

52 kDa

G3BP1 G3BP

Q13283

https://www.uniprot.org/uniprotkb/q13283

This Abmart monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human G3BP1

Mouse

Monoclonal

Mouse IgG

Antiviral defense #Innate immunity

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20°C, stable for one year from the date of shipment.