The catenins, α, and y, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin
associated protein, and since has been shown to associate with other members of the cadherin family, such as N- cadherin and P-cadherin. -catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. -catenin has also been found in complexes with the tumor suppressor protein APC. y-catenin, also known as plakoglobin, is a protein that binds with α-catenin and N-cadherin. It has been shown that the
transmembrane phosphatase PTPμ associates with catenin/cadherin complexes and may regulate complex signaling.

Catenin beta-1 (Beta-catenin) CTNNB1 CTNNB OK/SW-cl.35 PRO2286

Human, Mouse, Rat

WB,IF,IHC

Western blotting 1:1000 Immunofluorescence 1:200 Immunohistochemistry 1:200*

92kDa

CTNNB1 CTNNB OK/SW-cl.35 PRO2286

P35222

https://www.uniprot.org/uniprotkb/p35222

This Abmart monoclonal antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to carboxy-terminal residues of human -catenin.

Mouse

Monoclonal

Mouse IgG1

-Catenin (44C6) Mouse mAb detects endogenous levels of total -catenin protein.

Cell adhesion

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20°C, stable for one year from the date of shipment.

#M21001 Goat Anti-Mouse IgG-HRP

AB_2920853