The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]

Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form] ACTA1 ACTA

Human

WB

Western blotting 1:1000-1:10000

42

actin

P68133

https://www.uniprot.org/uniprotkb/p68133

Rabbit

Monoclonal

Rabbit

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20°C,stable for one year from the date of shipment.

AB_2936277