ACTH stimulates secretion of glucocorticoid steroid hormones from adrenal cortex cells, especially in the zona fasciculata of the adrenal glands. ACTH acts by binding to cell surface ACTH receptors, which are located primarily on adrenocortical cells of the adrenal cortex. The ACTH receptor is a seven-membrane-spanning G protein-coupled receptor. Upon ligand binding, the receptor undergoes conformation changes that stimulate the enzyme adenylyl cyclase, which leads to an increase in intracellular cAMP and subsequent activation of protein kinase A.

Mouse IgG2b

4E21

Synthetic peptide corresponding to the amino acids 1-39 of human ACTH, conjugated to a high molecular weight carrier

Human ACTH

Purified : IgG / Liquid
Purfication : Affinity chromatography on Protein G
Buffer system : 10 mM Hepes , 75 mM NaCl , pH 7.5, containing 0.05% Procline 300

ELISA                       1:10000-1:5000000

Human ACTH ELISA antibody pair 1.pdf

Human ACTH ELISA antibody pair 2.pdf

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Stored at -20°C or below until use. Avoid repeated freezing and thawing cycles.

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#T30003    Digoxin[2N7]   mAb (HRP Coujugated)