经典一抗-Anti-MNK1 Rabbit pAb

Datasheet

Background

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

Alternative Name

MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1) MKNK1 MNK1

Reactivity

Human,Mouse

Predicted Reactivity

Application

IHC,IF

Application Image

Recommanded Dilution

Mol Weight

52kD

Gene Symbol

MKNK1 MNK1

Uniprot

Q9BUB5

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Research Area

Translation regulation

Positive control

Conjugation

Modification

Purification

Formulation

Concentration

Buffer

产品介绍

Product Information

Description

MNK1rabbit polyclonal

Protein full nameMAP kinase-interacting serine/threonine-protein kinase 1

Synonyms

MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1, Mknk1, Mnk1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MNK1

IsotypeIgG
PurityAffinity purification
Subcellular location
Cytoplasm,Nucleus

Uniprot ID

Q9BUB5, O08605


Applications

ApplicationsIHC
IF
SpeciesHuman,MouseHuman,Mouse
Dilution1:1000-1:2000
1:1000-1:2000
Positive tissuelung cancer, liver cancer, colon cancer, colon, tonsil, brain
ovary, liver, brain striatum, lung

Background

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G.


Images

Immunohistochemistry analysis of paraffin-embedded human lung cancerusing
MNK1 (T611286M) at dilution of 1:1000



Immunohistochemistry analysis of paraffin-embedded human liver cancerusing
MNK1 (T611286M) at dilution of 1:1000

Immunohistochemistry analysis of paraffin-embedded human colon cancerusing
MNK1 (T611286M) at dilution of 1:1000

Immunohistochemistry analysis of paraffin-embedded human colonusing
MNK1 (T611286M) at dilution of 1:1300

Immunohistochemistry analysis of paraffin-embedded human tonsilusing
MNK1 (T611286M) at dilution of 1:1300

Immunohistochemistry analysis of paraffin-embedded mouse brainusing
MNK1 (T611286M) at dilution of 1:1300

Immunofluorescentanalysis ofparaformaldehyde-fixedhuman ovaryusing
MNK1 (T611286M) at dilution of 1:1300

Immunofluorescentanalysis ofparaformaldehyde-fixedhuman liverusing
MNK1 (T611286M) at dilution of 1:1300

Immunofluorescentanalysis ofparaformaldehyde-fixedmouse brain striatumusing MNK1 (T611286M) at dilution of 1:1300

Immunofluorescentanalysis ofparaformaldehyde-fixedmouse lungusing
MNK1 (T611286M) at dilution of 1:1300

Storage

StorageStore at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage BufferPBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE: This product is intended for research only.

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

T611286

货号 规格 价格(¥)
T611286M 100ul
T611286S 50ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13162017139(微信同号)

技术支持:15618194176(微信同号)

总机:021-34695901

南方经销商负责:手机13122837132(微信同号)          
北方及西南经销商负责:手机13122150513(微信同号)

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