Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

Heterogeneous nuclear ribonucleoprotein L (hnRNP L) HNRNPL HNRPL P/OKcl.14

Human

WB,IP,FACS

Western blotting 1:1000-1:5000 Immunoprecipitation 10 tests FACS 1:100-1:200

64 kDa

HNRNPL HNRPL P/OKcl.14

P14866

https://www.uniprot.org/uniprotkb/p14866

This Abmart monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human HNRPL

Mouse

Monoclonal

Mouse IgG

mRNA processing

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20°C, stable for one year from the date of shipment.